Hotels in Otay Mesa, San Diego
Search hundreds of travel sites at once for hotels in Otay Mesa
...and more
Here is why travelers choose KAYAK
Free to useThere are no hidden charges or fees.
Filter your dealsFilter by free cancellation, free breakfast and more.
Millions of reviewsCheck ratings based on millions of real guest reviews.
Best hotels in Otay Mesa (San Diego)
Most recommended Otay Mesa hotels
Holiday Inn Express & Suites San Diego Otay Mesa
Otay Mesa₪753+
₪753+
Free Wi-Fi
Pool
Air Conditioning
Quality Suites San Diego Otay Mesa
Otay Mesa₪442+
₪442+
Parking
Free Wi-Fi
Pool
Air Conditioning
AAAmazing San Diego! Suite just for you/yours!
Otay Mesa₪1,188+
₪1,188+
Free Wi-Fi
Pool
Air Conditioning
How much is a Otay Mesa hotel?
Here are our most popular & best value hotels2 stars and below
When to book a hotel in Otay Mesa
Price per night / 3-star hotel. Prices are not fixed and may vary with time.
Average nightly price per month
Average nightly price
Top tips for finding a hotel deal in Otay Mesa
- For the lowest prices, try to book your Otay Mesa hotel more than 90 days before your stay.
- Not sure just how much there is to see and do in Otay Mesa? KAYAK users usually book their hotel here for 3 days.
FAQs when booking a hotel in Otay Mesa
What are the best hotels in Otay Mesa?
Otay Mesa is a great part of San Diego to make your base. If you’re staying in Otay Mesa area then Quality Suites San Diego Otay Mesa, Holiday Inn Express & Suites San Diego Otay Mesa, and AAAmazing San Diego! Suite just for you/yours! are all recommended on KAYAK.
How much does a hotel in Otay Mesa (San Diego) cost?
The average price for a hotel room in Otay Mesa is ₪514 but our users have found deals for as low as ₪416. However, hotel prices in Otay Mesa vary a lot depending on the type of hotel, the time of year and more factors.
Where to stay in Otay Mesa?
Our map will help you find the perfect hotel in Otay Mesa, San Diego by showing you the exact location of each hotel.